IGF-1 DES

IGF-1 DES is a naturally occurring, endogenous protein, as well as drug, and truncated analog of insulin-like growth factor 1 (IGF-1 DES) des IGF-1 lacks the first three amino acids at the N-terminus of IGF-1 (for a total of 67 amino acids, relative to the 70 of IGF-1). As a result of this difference, it has considerably reduced binding to the Insulin-like growth factor-binding proteins (IGFBPs) and enhanced potency (about 10-fold in vivo) relative to IGF-1 DES